7-酮石胆酸是一种胆汁酸衍生物，化学名为3α-羟基-7-氧代-5β-胆烷酸，CAS号为4651-67-6，分子式C24H38O4,分子量390.56。7-酮石胆酸是肠道细菌（如梭菌、乳酸杆菌和双歧杆菌）代谢胆汁酸的产物，能够抑制内源性胆汁酸合成和胆汁中胆固醇的分泌，可能参与肝胆疾病的病理调节。作为熊去氧胆酸的和奥贝胆酸的关键中间体，用于治疗胆结石、胆汁淤积性肝病等。
7-Keto lithocholic acid is a bile acid derivative, with the chemical name of 3α-hydroxy-7-oxo-5β-cholanoic acid, CAS number 4651-67-6, molecular formula C24H38O4, and molecular weight 390.56. 7-Keto lithocholic acid is a product of bile acid metabolism by intestinal bacteria (such as Clostridium, Lactobacillus and Bifidobacterium), which can inhibit endogenous bile acid synthesis and cholesterol secretion in bile, and may be involved in the pathological regulation of hepatobiliary diseases. As a key intermediate of ursodeoxycholic acid and obeticholic acid, it is used to treat gallstones, cholestatic liver disease, etc.
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