Liraglutide for Injection: High-Quality GLP-1 Receptor Agonist for Diabetes Management

Liraglutide is a long-acting glucagon-like peptide-1 (GLP-1) analog with 97% amino acid sequence homology to endogenous GLP-1. It functions through several key mechanisms:

1. Insulin Secretion: Liraglutide binds to GLP-1 receptors on pancreatic beta cells, promoting glucose-dependent insulin secretion to lower blood glucose levels.
2. Inhibition of Glucagon Secretion: It reduces the secretion of glucagon, thereby decreasing hepatic glucose production.
3. Delayed Gastric Emptying: Liraglutide slows down gastric emptying, reducing the rapid absorption of glucose from the gastrointestinal tract.
4. Appetite Regulation: By acting on the central appetite regulation centers in the brain, liraglutide suppresses appetite and increases satiety, leading to reduced food intake.
5. Beta-Cell Protection: Liraglutide helps protect pancreatic beta-cell function by promoting beta-cell proliferation and reducing apoptosis.

Applications

Liraglutide is primarily used for:

1. Type 2 Diabetes Treatment: It helps regulate blood glucose levels, reduces HbA1c, and lowers the risk of diabetes-related complications.
2. Obesity Management: Approved for the treatment of obesity, liraglutide aids in weight loss by suppressing appetite and reducing food intake.
3. Cardiovascular Protection: Some studies suggest that liraglutide may offer cardiovascular benefits.

Dosage Instructions

1. For Type 2 Diabetes:The initial dose is typically 0.6 mg once daily, administered via subcutaneous injection.After one week, the dose can be increased to 1.2 mg daily, with a maximum recommended dose of 1.8 mg per day.
2. For Obesity Treatment:The usual dose is 3.0 mg once daily, administered via subcutaneous injection.It is recommended to inject at the same time each day to maintain stable drug levels.

Storage

1. Unopened Liraglutide: Should be stored refrigerated (2°C to 8°C) and protected from freezing.
2. Opened Liraglutide: Can be stored at room temperature (not exceeding 25°C) for up to 28 days after opening.
3. Avoid exposure to direct sunlight and high temperatures, and keep the medication out of reach of children and pets.