| Tetracycline Hcl | CAS:64-75-5 | |
| MF: C22H24N2O8.HCl | MSDS and COA: Aviable | |
| MW: 480.90 | EINECS: 200-593-8 | |
| Description: | 1. Tetracycline hydrochloride is a type of broad-spectrum antibiotics 2.Tetracycline hydrochloride can be used for bacillary dysentery (bacillary dysentery), trachoma, whooping cough, purulent meningitis, peritonitis, pneumonia, osteomyelitis. Scarlet fever, typhus, urinary tract infections, skin infections, otitis media, amoebic dysentery, biliary tract infections, intestinal infections, sepsis and so on 3. Tetracycline hydrochloride can be used in penicillin-resistant strains of infections, penicillin allergy | |
Certificate of Analysis
| Tests | Specification | Results | |
| BP | EP | ||
| Characters | Yellow crystalline powder | Yellow crystalline powder | Yellow crystalline powder |
| Soluble in **, slightly soluble in ethanol(96%),practically insoluble in acetone | Soluble in **, slightly soluble in ethanol(96%),practically insoluble in acetone | conforms | |
| Identification | |||
| A.TLC | Conforms to the reference | Positive reaction | |
| B.Color reaction | To about 2mg add 5ml of sulphuric add the solution to 2.5ml of **, the color becomes yellow | Positive reaction | |
| C. Chlorides | Reactions of chlorides | Positive reaction | |
| Acidity(PH) | 1.8-2.8 | 2.29 | |
| Specific optional rotation(dried) | -240°~-255° | 246° | |
| Loss on drying | ≤2.0% | 0.19% | |
| Heavy metals | Not more than 50ppm | <40ppm | |
| Sulphated ash | ≤0.50% | 0.04% | |
| Related substances | |||
| 4-epitetracycline | ≤3.0% | 1.50% | |
| 4-epianhydrotetracycline | ≤0.50% | ND | |
| anhydrotetracycline | ≤0.50% | 0.12% | |
| 2-acetyl-2-decarbamoyltetracycline | ≤1.50% | 0.56% | |
| Assay | 95%-102.0% | 97.80% | |
| Residual solvent | |||
| Acetone(GC) | ≤100ppm | 23ppm | |
| n-butanoL(GC) | ≤3000ppm | 1960ppm | |
| Microbiological examination | |||
| TAMC | ≤1000cfu/g | <10cfu/g | |
| TYMC | ≤100cfu/g | <10cfu/g | |
| E. coli. | absense | absense | |
| Conclusion | The results conform with the specifications. | ||
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